Type 1 diabetes

Type 1 diabetes occurs due to a deficiency in insulin production by the pancreas.  This is most commonly due to an autoimmune cause, where the body produces antibodies to the insulin-producing cells in the pancreas, leading to the destruction of these cells and resultant insulin deficiency.

The onset of Type 1 diabetes can occur in childhood or adulthood, and a slowly progressive form, know as Latent Autoimmune Diabetes of Adulthood (LADA), which can initially present like type 2 diabetes, but eventually results in insulin deficiency requiring insulin therapy, can also occur in adulthood.

There are various conditions, such as acute and chronic pancreatitis and surgical pancreatectomy, which can result in insulin-deficient diabetes requiring insulin therapy for treatment. 

Insulin therapy is required to treat type 1 diabetes.  At present, insulin is only available in injectable form. Insulins and diabetes technology to assist with type 1 diabetes management have progressed considerably over the last 5-10 years. Although lifestyle factors do not contribute to the development of type 1 diabetes, adjusting certain lifestyle factors can assist in managing blood glucose levels.

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